Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | GRM6 | O15303 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30564259 | 0.85 | ALDH1A1 (0.56) | GRM5MEN1KMT2AFAAHCNR2 | |
| SCHEMBL30478998 | 0.84 | NPC1 (0.58) | GRM5MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL30479071 | 0.84 | MCHR1 (0.49) | GRM5MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL1711687 | 0.84 | ALDH1A1 (0.63) | GRM5MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL29530916 | 0.84 | ALDH1A1 (0.63) | GRM5MEN1KMT2AALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL31722313 | 0.83 | ALDH1A1 (0.62) | GRM5MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL17067333 | 0.81 | L3MBTL1 (0.74) | GRM5MEN1KMT2AFAAHCNR2 | |
| SCHEMBL30938343 | 0.81 | ALDH1A1 (0.57) | GRM5MEN1KMT2AFAAHCNR2 | |
| SCHEMBL30479051 | 0.81 | EZH2 (0.55) | MEN1KMT2AFAAHL3MBTL1NPC1 | |
| SCHEMBL25034788 | 0.80 | MEN1 (0.51) | MEN1KMT2ACNR2L3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119790057-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2025-04-08 | — | — | CN | disclosed |
| CN-116322700-B | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-08-20 | — | — | CN | disclosed |
| CN-118076607-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-05-24 | — | — | CN | disclosed |
| CN-116261458-B | PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-05-24 | — | — | CN | disclosed |