Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 4/20 | 0.57 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.45 |
| ▸ | WNT1 | P04628 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17409811 | 0.84 | SMYD3 (0.70) | SMYD3KMT2AMEN1SIGMAR1CTDSP1 | |
| SCHEMBL30564259 | 0.81 | ALDH1A1 (0.56) | KMT2AMEN1MAPK1 | |
| SCHEMBL10263884 | 0.78 | SMYD3 (0.86) | SMYD3KMT2AL3MBTL1 | |
| SCHEMBL24529101 | 0.76 | SMYD3 (0.78) | SMYD3KMT2AMEN1L3MBTL1 | |
| SCHEMBL21257402 | 0.76 | SMYD3 (0.78) | SMYD3KMT2AMEN1L3MBTL1 | |
| SCHEMBL25685444 | 0.74 | SMYD3 (0.63) | SMYD3KMT2ASIGMAR1DRD2DRD4 | |
| SCHEMBL24529113 | 0.74 | SMYD3 (0.66) | SMYD3KMT2AMEN1 | |
| SCHEMBL24529100 | 0.73 | SMYD3 (0.72) | SMYD3 | |
| SCHEMBL21489836 | 0.73 | SMYD3 (1.00) | SMYD3 | |
| SCHEMBL17409822 | 0.73 | SMYD3 (0.72) | SMYD3KMT2AL3MBTL1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116527-A1 | COMPOUND AS FAK INHIBITOR AND USE THEREOF | 微境生物医药科技(上海)有限公司 | 2023-06-29 | — | — | WO | disclosed |