Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | PPP3CB | P16298 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13222487 | 1.00 | CTSS (0.49) | CTSSCYP3A4CTSBPPP3CB | |
| SCHEMBL3048024 | 1.00 | CTSS (0.49) | CTSSCYP3A4CTSBPPP3CB | |
| SCHEMBL3044768 | 0.95 | CTSB (0.47) | CTSSCYP3A4CTSBPPP3CB | |
| SCHEMBL13222489 | 0.95 | CTSB (0.47) | CTSSCYP3A4CTSBPPP3CB | |
| SCHEMBL13222475 | 0.95 | CTSS (0.46) | CTSSCYP3A4CTSBPPP3CB | |
| SCHEMBL3037617 | 0.95 | CTSS (0.46) | CTSSCYP3A4CTSBPPP3CB | |
| SCHEMBL3037623 | 0.95 | CTSS (0.46) | CTSSCYP3A4CTSBPPP3CB | |
| SCHEMBL3047105 | 0.95 | CYP3A4 (0.46) | CTSSCYP3A4CTSBPPP3CB | |
| SCHEMBL3047109 | 0.95 | CYP3A4 (0.46) | CTSSCYP3A4CTSBPPP3CB | |
| SCHEMBL3047112 | 0.95 | CYP3A4 (0.46) | CTSSCYP3A4CTSBPPP3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8614180-B2 | 4-amino-4-oxobutanoyl peptides as inhibitors of viral replication | ACHILLION PHARMACEUTICALS, INC. (US) | 2013-12-24 | — | — | US | disclosed |
| US-20100216725-A1 | 4-AMINO-4-OXOBUTANOYL PEPTIDES AS INHIBITORS OF VIRAL REPLICATION | ACHILLION PHARMACEUTICALS, INC. (US) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216725-A1 | 4-AMINO-4-OXOBUTANOYL PEPTIDES AS INHIBITORS OF VIRAL REPLICATION | ZC3HAV1, VIP, O60361 | CTSS 2219/4885CYP3A4 1615/4885CTSB 1193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.