Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL615257 | 0.87 | SUV39H2 (0.32) | DGAT1 | |
| SCHEMBL29053468 | 0.83 | — | — | |
| SCHEMBL30480731 | 0.83 | — | — | |
| SCHEMBL29053466 | 0.83 | — | — | |
| SCHEMBL29053464 | 0.79 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL615297 | 0.79 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL615227 | 0.78 | F11 (0.33) | DGAT1 | |
| SCHEMBL614413 | 0.77 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL29053524 | 0.77 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL615763 | 0.77 | DGAT1 (0.33) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107973809-B | Macrocyclic compounds as factor XIA inhibitors | 百时美施贵宝公司 | 2023-06-30 | — | — | CN | disclosed |