Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.55 |
| ▸ | MAP2K4 | P45985 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | MAPK6 | Q16659 | 3/20 | 0.51 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.51 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.47 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 7/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | MAPKAPK3 | Q16644 | 2/20 | 0.45 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25279396 | 1.00 | TRPA1 (0.55) | TRPA1MAP2K4MAPK1MAPK6MAPKAPK5 | |
| SCHEMBL25241733 | 0.86 | MAP2K4 (0.56) | TRPA1MAP2K4MAPK1MAPK6MAPKAPK5 | |
| SCHEMBL30481232 | 0.86 | MAP2K4 (0.56) | TRPA1MAP2K4MAPK1MAPK6MAPKAPK5 | |
| SCHEMBL2662677 | 0.80 | TRPA1 (0.56) | TRPA1MAP2K4MAPK1MAPK6MAPKAPK5 | |
| SCHEMBL30586177 | 0.79 | TRPA1 (0.55) | TRPA1MAP2K4MAPK1MAPK6MAPKAPK5 | |
| SCHEMBL13122227 | 0.79 | TRPA1 (0.55) | TRPA1MAP2K4MAPK1MAPK6MAPKAPK5 | |
| SCHEMBL1513093 | 0.79 | TRPA1 (0.55) | TRPA1MAP2K4MAPK1MAPK6MAPKAPK5 | |
| SCHEMBL24076862 | 0.78 | MAPT (0.47) | TRPA1MAP2K4MAPK1MAPK6MAPKAPK5 | |
| SCHEMBL10220256 | 0.76 | KIF11 (0.56) | TRPA1MAP2K4MAPK1MAPK6MAPKAPK5 | |
| SCHEMBL30548016 | 0.76 | MAP2K4 (0.56) | MAP2K4MAPK1MAPK6MAPKAPK3MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122060008-A | Indazole alkaloid derivative and preparation method and application thereof | 江西师范大学 | 2026-05-19 | — | — | CN | disclosed |
| EP-4452936-A2 | INDOLES, INDAZOLES, AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | The Katholieke Universiteit Leuven (BE) | 2024-10-30 | — | — | EP | disclosed |
| WO-2023122782-A2 | INDOLES, INDAZOLES, AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | THE KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-06-29 | — | — | WO | disclosed |