Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CPB1 | P15086 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25375808 | 0.97 | CASP3 (0.47) | CASP3ALDH1A1GAACPB1TSHR | |
| SCHEMBL30482174 | 0.94 | CASP3 (0.53) | CASP3ALDH1A1GAACPB1TSHR | |
| SCHEMBL30963623 | 0.94 | CASP3 (0.53) | CASP3ALDH1A1GAACPB1TSHR | |
| SCHEMBL19086685 | 0.94 | CASP3 (0.53) | CASP3ALDH1A1GAACPB1TSHR | |
| SCHEMBL25376757 | 0.88 | CASP3 (0.48) | CASP3ALDH1A1GAACPB1TSHR | |
| SCHEMBL5896895 | 0.87 | ALDH1A1 (0.57) | CASP3ALDH1A1GAACPB1TSHR | |
| SCHEMBL5896898 | 0.87 | ALDH1A1 (0.57) | CASP3ALDH1A1GAACPB1TSHR | |
| SCHEMBL31064941 | 0.87 | ALDH1A1 (0.57) | CASP3ALDH1A1GAACPB1TSHR | |
| SCHEMBL5897658 | 0.87 | ALDH1A1 (0.57) | CASP3ALDH1A1GAACPB1TSHR | |
| SCHEMBL5897664 | 0.87 | ALDH1A1 (0.57) | CASP3ALDH1A1GAACPB1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469438-A1 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023146987-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |