Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25373830 | 1.00 | RECQL (0.54) | RECQLCYP2D6CYP2C9CYP2C19MEN1 | |
| SCHEMBL25373467 | 0.92 | RECQL (0.47) | RECQLCYP2D6CYP2C9CYP2C19MEN1 | |
| SCHEMBL25375508 | 0.86 | MEN1 (0.58) | RECQLMEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL25375460 | 0.86 | L3MBTL1 (0.60) | RECQLMEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL30482189 | 0.85 | RECQL (0.51) | RECQLCYP2D6CYP2C9CYP2C19MEN1 | |
| SCHEMBL25377248 | 0.85 | RECQL (0.51) | RECQLCYP2D6CYP2C9CYP2C19MEN1 | |
| SCHEMBL25377677 | 0.84 | SMN1; SMN2 (0.50) | MEN1KMT2AL3MBTL1TSHRALDH1A1 | |
| SCHEMBL25378936 | 0.84 | L3MBTL1 (0.46) | MEN1KMT2AL3MBTL1TSHRALDH1A1 | |
| SCHEMBL25375114 | 0.79 | KDM4E (0.54) | MEN1KMT2AL3MBTL1TSHRALDH1A1 | |
| SCHEMBL25376675 | 0.78 | TRPM8 (0.54) | RECQLMEN1KMT2AL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469438-A1 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023146987-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |