Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC5R | P33032 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | MC1R | Q01726 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2865597 | 1.00 | MC5R (0.70) | MC5RMAPK1KMT2AMEN1MC1R | |
| SCHEMBL6008064 | 0.90 | MC5R (0.70) | MC5RMAPK1KMT2AMEN1MC1R | |
| SCHEMBL3242373 | 0.86 | MC5R (0.67) | MC5RMAPK1KMT2AMEN1MC1R | |
| SCHEMBL21296202 | 0.86 | MC5R (0.67) | MC5RMAPK1KMT2AMEN1MC1R | |
| SCHEMBL15131007 | 0.86 | MAPK1 (0.67) | MC5RMAPK1KMT2AMEN1MC1R | |
| SCHEMBL15130991 | 0.86 | MC5R (0.67) | MC5RMAPK1KMT2AMEN1MC1R | |
| SCHEMBL9080754 | 0.85 | MC5R (0.66) | MC5RMAPK1KMT2AMEN1MC1R | |
| Hydrochloric Acid SCHEMBL31146828 | 0.84 | MC5R (0.65) | MC5RMAPK1KMT2AMEN1MC1R | |
| SCHEMBL2343213 | 0.84 | HPGD (0.62) | MC5RMAPK1KMT2AMEN1HPGD | |
| SCHEMBL15131004 | 0.84 | CA12 (0.68) | MC5RMAPK1KMT2AMEN1MC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469438-A1 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023146987-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |