Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | CD38 | P28907 | 3/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27164862 | 1.00 | PIM1 (0.45) | PIM1DYRK1ADYRK2DYRK1BCD38 | |
| SCHEMBL24568619 | 0.79 | CYP2A6 (0.51) | PIM1DYRK1ADYRK2DYRK1BCD38 | |
| SCHEMBL24567811 | 0.75 | TBXAS1 (0.41) | PIM1DYRK1ADYRK2DYRK1BCD38 | |
| SCHEMBL7430359 | 0.74 | CYP11B1 (0.47) | ADORA2A | |
| SCHEMBL5088040 | 0.73 | KDM4E (0.61) | PIM1DYRK1ADYRK2DYRK1BTBXAS1 | |
| SCHEMBL15624391 | 0.73 | TDP1 (0.44) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL28273959 | 0.73 | HDAC4 (0.43) | PIM1DYRK1ADYRK2DYRK1BCD38 | |
| SCHEMBL28416665 | 0.73 | PIM1 (0.41) | PIM1DYRK1ADYRK2DYRK1BCD38 | |
| SCHEMBL15638356 | 0.73 | CD38 (0.46) | PIM1DYRK1ADYRK2DYRK1BCD38 | |
| SCHEMBL19302641 | 0.72 | PIM1 (0.51) | PIM1DYRK1ADYRK2DYRK1BCD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469035-A1 | IMIDAZOPYRIDINE INHIBITORS OF TYROSINE KINASE | Bridgene Biosciences, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023146786-A1 | IMIDAZOPYRIDINE INHIBITORS OF TYROSINE KINASE | BRIDGENE BIOSCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |