Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL988835 | 0.74 | CA1 (0.36) | FFAR3LCKFYN | |
| SCHEMBL988834 | 0.74 | CA1 (0.36) | FFAR3LCKFYN | |
| SCHEMBL14690127 | 0.74 | CA1 (0.36) | FFAR3LCKFYN | |
| SCHEMBL9156418 | 0.71 | LDHA (0.33) | ALDH1A1TSHR | |
| SCHEMBL9156417 | 0.71 | LDHA (0.33) | ALDH1A1TSHR | |
| SCHEMBL500714 | 0.71 | FFAR3 (0.35) | ALDH1A1TSHRFFAR3LCKFYN | |
| SCHEMBL936585 | 0.71 | FFAR3 (0.35) | ALDH1A1TSHRFFAR3LCKFYN | |
| SCHEMBL11125449 | 0.71 | FFAR3 (0.35) | ALDH1A1TSHRFFAR3LCKFYN | |
| SCHEMBL10604698 | 0.69 | — | — | |
| SCHEMBL26929225 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4370506-A1 | PYRAZINE COMPOUNDS AS INHIBITORS OF FLT3 | Biomea Fusion, Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| WO-2023129667-A1 | PYRAZINE COMPOUNDS AS INHIBITORS OF FLT3 | BIOMEA FUSION, INC. (US) | 2023-07-06 | — | — | WO | disclosed |