Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9156418 | 1.00 | LDHA (0.33) | LDHALDHBCA1CA2CA9 | |
| SCHEMBL988834 | 0.95 | CA1 (0.36) | LDHALDHBCA1CA2CA9 | |
| SCHEMBL14690127 | 0.95 | CA1 (0.36) | LDHALDHBCA1CA2CA9 | |
| SCHEMBL988835 | 0.95 | CA1 (0.36) | LDHALDHBCA1CA2CA9 | |
| Boric Acid SCHEMBL31404443 | 0.84 | LMNA (0.31) | TSHR | |
| Boric Acid SCHEMBL31404421 | 0.84 | LMNA (0.31) | TSHR | |
| SCHEMBL132786 | 0.78 | — | — | |
| SCHEMBL11129009 | 0.78 | LDHA (0.50) | LDHALDHBGABRR1ALDH1A1 | |
| SCHEMBL15546673 | 0.75 | — | — | |
| SCHEMBL15547842 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557272-B1 | PROCESS FOR THE PREPARATION OF DIFLUOROMALEIC ANHYDRIDE AND INTERMEDIATE COMPOUNDS PRODUCED THEREBY | DU PONT (US) | 1995-03-08 | — | — | EP | disclosed |
| EP-0557272-A1 | PROCESS FOR THE PREPARATION OF DIFLUOROMALEIC ANHYDRIDE AND INTERMEDIATE COMPOUNDS PRODUCED THEREBY. | DU PONT (US) | 1993-09-01 | — | — | EP | disclosed |
| US-5235069-A | Process for the preparation of difluoromaleic anhydride and intermediate compounds produced thereby | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-08-10 | — | — | US | disclosed |
| WO-1992008710-A1 | PROCESS FOR THE PREPARATION OF DIFLUOROMALEIC ANHYDRIDE AND INTERMEDIATE COMPOUNDS PRODUCED THEREBY | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |
| US-5112993-A | Process for the preparation of difluoromaleic anhydride | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-05-12 | — | — | US | disclosed |