Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 8/20 | 0.37 |
| ▸ | CA2 | P00918 | 8/20 | 0.37 |
| ▸ | CA9 | Q16790 | 6/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.36 |
| ▸ | P4HB | P07237 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2932908 | 0.83 | P4HB (0.50) | HIF1ACA1CA2CA9P4HB | |
| SCHEMBL14995786 | 0.76 | HIF1A (0.45) | HIF1ACA1CA2CA9P4HB | |
| SCHEMBL18241170 | 0.76 | CSNK2A1 (0.47) | HIF1ACA1CA2CA9P4HB | |
| SCHEMBL30483081 | 0.75 | HIF1A (0.46) | HIF1ACA1CA2CA9P4HB | |
| SCHEMBL25981432 | 0.75 | LIG1 (0.54) | CA1CA2CA9P4HBCA12 | |
| SCHEMBL476909 | 0.75 | LPL (0.53) | CA1CA2CA9P4HBALDH1A1 | |
| SCHEMBL25994215 | 0.74 | CSNK2A1 (0.50) | CA1CA2P4HBALDH1A1PKM | |
| SCHEMBL16828504 | 0.74 | CA1 (0.48) | HIF1ACA1CA2CA9P4HB | |
| SCHEMBL4745737 | 0.73 | ESR2 (0.41) | HIF1ACA1CA2CA9CA12 | |
| SCHEMBL18252711 | 0.72 | CA1 (0.53) | HIF1ACA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4168411-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV Pharmaceuticals, Inc. (US) | 2023-04-26 | — | — | EP | disclosed |