SCHEMBL30484136

SCHEMBL30484136

Nc1ccc(Cl)cc1C(=O)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.67
MAPT P10636 5/20 0.64
POLB P06746 2/20 0.64
GAA P10253 1/20 0.63
GFER P55789 1/20 0.63
KMT2A Q03164 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
ALDH1A1 P00352 3/20 0.56
HTT P42858 2/20 0.56
MITF O75030 1/20 0.56
HSP90AA1 P07900 1/20 0.56
ATM Q13315 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
TLR9 Q9NR96 1/20 0.56
S100B P04271 1/20 0.56
GABRP O00591 1/20 0.55
GABRD O14764 1/20 0.55
GABRA1 P14867 1/20 0.55
GABRB1 P18505 1/20 0.55
GABRG2 P18507 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31000389 1.00 RECQL (0.67) RECQLMAPTPOLBGAAGFER
SCHEMBL145366 1.00 RECQL (0.67) RECQLMAPTPOLBGAAGFER
Hydrazine SCHEMBL11821861 0.98 RECQL (0.65) RECQLMAPTPOLBGAAGFER
Hydrochloric Acid SCHEMBL27581315 0.98 RECQL (0.65) RECQLMAPTPOLBGAAGFER
Acetamide SCHEMBL16335345 0.93 RECQL (0.59) RECQLMAPTPOLBGAAGFER
SCHEMBL6351799 0.91 RECQL (0.64) RECQLMAPTPOLBGAAGFER
SCHEMBL28751447 0.91 RECQL (0.56) RECQLMAPTPOLBGAAGFER
SCHEMBL12653273 0.87 RECQL (0.60) RECQLMAPTPOLBGAAGFER
SCHEMBL31366555 0.87 MAPT (0.61) RECQLMAPTPOLBGAAALDH1A1
SCHEMBL1041696 0.87 MAPT (0.61) RECQLMAPTPOLBGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116377458-A Method for electrochemically synthesizing quinazoline derivative 安徽科技学院 2023-07-04 CN claimed
EP-4608817-A1 COMPOUNDS AND METHODS FOR TREATING CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-09-03 EP disclosed
US-20250213700-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR CELL-SPECIFIC PHARMACOLOGY FOX CHASE CHEMICAL DIVERSITY CENTER, INC. 2025-07-03 US disclosed
CN-118388387-B Synthesis method of indole compounds 无锡学院 2025-03-14 CN disclosed
CN-119072467-A Novel diazapine compounds targeting yellow fever virus non-structural 4B (NS 4B) protein and methods of use thereof 巴鲁克斯布伦博格研究所 2024-12-03 CN disclosed
CN-118388387-A Synthesis method of indole compounds 无锡学院 2024-07-26 CN disclosed
CN-118027042-A Organic electroluminescent compound and organic electroluminescent device comprising the same 罗门哈斯电子材料韩国有限公司 2024-05-14 CN disclosed
WO-2024091450-A1 COMPOUNDS AND METHODS FOR TREATING CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-05-02 WO disclosed
CN-111094508-B Organic electroluminescent compound and organic electroluminescent device comprising the same 罗门哈斯电子材料韩国有限公司 2024-03-08 CN disclosed
CN-117088888-A Preparation method of alprazolam and impurity LAP thereof 山东安信制药有限公司 2023-11-21 CN disclosed
CN-116377458-A Method for electrochemically synthesizing quinazoline derivative 安徽科技学院 2023-07-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250213700-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR CELL-SPECIFIC PHARMACOLOGY DDT, ABCG2, CES2 RECQL 2139/4885MAPT 2568/4885POLB 2859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.