Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.64 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.64 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL695880 | 1.00 | CYP4F2 (0.64) | CYP4F2CYP4A11MMP1CYP3A4TAAR1 | |
| SCHEMBL1239104 | 0.85 | TAAR1 (0.51) | CYP4F2CYP4A11CYP3A4TAAR1TSHR | |
| SCHEMBL2382627 | 0.84 | HTT (0.50) | CYP4F2CYP4A11MAPK1NPC1POLB | |
| SCHEMBL2890956 | 0.82 | CYP4F2 (0.57) | CYP4F2CYP4A11NPC1POLBRAB9A | |
| SCHEMBL4159177 | 0.82 | TNKS2 (0.56) | TAAR1TSHRMAPK1POLBLMNA | |
| SCHEMBL2432106 | 0.82 | PTGS2 (0.52) | CYP4F2CYP4A11TAAR1TSHRMAPK1 | |
| SCHEMBL29997296 | 0.81 | CA2 (0.68) | CYP3A4NPC1POLBRAB9ACA2 | |
| SCHEMBL28170408 | 0.81 | CA2 (0.68) | CYP3A4NPC1POLBRAB9ACA2 | |
| SCHEMBL119395 | 0.81 | CA2 (0.68) | CYP3A4NPC1POLBRAB9ACA2 | |
| SCHEMBL31163873 | 0.81 | CYP4F2 (0.60) | CYP4F2CYP4A11TSHRPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069700-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |