Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | WEE1 | P30291 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21349652 | 1.00 | PGR (0.33) | PGRAPPBACE1KDM1AWEE1 | |
| SCHEMBL24881003 | 0.95 | GAA (0.31) | PGR | |
| SCHEMBL24880941 | 0.90 | AR (0.30) | — | |
| SCHEMBL23364922 | 0.90 | AR (0.30) | — | |
| SCHEMBL21350109 | 0.90 | AR (0.30) | — | |
| SCHEMBL23364855 | 0.82 | WEE1 (0.33) | APPBACE1WEE1 | |
| SCHEMBL21332774 | 0.82 | WEE1 (0.33) | APPBACE1WEE1 | |
| SCHEMBL29828627 | 0.82 | WEE1 (0.33) | APPBACE1WEE1 | |
| SCHEMBL30594670 | 0.82 | WEE1 (0.33) | APPBACE1WEE1 | |
| SCHEMBL17441194 | 0.81 | KDM1A (0.34) | PGRKDM1AWEE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720541-A | Substituted 1, 2-dihydro-3H-pyrazolo [3,4-d ] pyrimidin-3-ones | 里科瑞尔姆IP控股有限责任公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-111902413-B | Substituted 1, 2-dihydro-3H-pyrazolo [3,4-d ] pyrimidin-3-ones | 里科瑞尔姆IP控股有限责任公司 | 2023-10-17 | — | — | CN | disclosed |
| CN-112142748-B | Pyrazolopyrimidine compound, and preparation method and application thereof | 上海医药集团股份有限公司 | 2023-07-04 | — | — | CN | disclosed |