SCHEMBL23364855

SCHEMBL23364855

CC[C@@]1(O)CCCc2ccc(Br)nc21

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
WEE1 P30291 1/20 0.33
APP P05067 1/20 0.31
BACE1 P56817 1/20 0.31
MAP3K14 Q99558 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29828627 1.00 WEE1 (0.33) WEE1APPBACE1MAP3K14
SCHEMBL30594670 1.00 WEE1 (0.33) WEE1APPBACE1MAP3K14
SCHEMBL21332774 1.00 WEE1 (0.33) WEE1APPBACE1MAP3K14
SCHEMBL24881036 0.95 GRIN2D (0.33) WEE1MAP3K14
SCHEMBL21334000 0.90 MAP3K14 (0.32) WEE1MAP3K14
SCHEMBL21332753 0.90 MAP3K14 (0.32) WEE1MAP3K14
SCHEMBL21349674 0.90 MAP3K14 (0.32) WEE1MAP3K14
SCHEMBL25100755 0.84 NR3C1 (0.34) WEE1MAP3K14
SCHEMBL23364936 0.84 NR3C1 (0.34) WEE1MAP3K14
SCHEMBL23364932 0.84 NR3C1 (0.34) WEE1MAP3K14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260028363-A1 CHIRAL SYNTHESIS OF A TERTIARY ALCOHOL RECURIUM IP HOLDINGS LLC (US) 2026-01-29 US disclosed
US-12410204-B2 Chiral synthesis of a tertiary alcohol RECURIUM IP HOLDINGS, LLC (US) 2025-09-09 US disclosed
US-20230002426-A1 CHIRAL SYNTHESIS OF A TERTIARY ALCOHOL RECURIUM IP HOLDINGS, LLC 2023-01-05 US disclosed
US-20230002426-A1 CHIRAL SYNTHESIS OF A TERTIARY ALCOHOL RECURIUM IP HOLDINGS, LLC 2023-01-05 US disclosed
EP-4045486-A1 CHIRAL SYNTHESIS OF A TERTIARY ALCOHOL Recurium IP Holdings, LLC (US) 2022-08-24 EP disclosed
WO-2021097139-A1 CHIRAL SYNTHESIS OF A TERTIARY ALCOHOL RECURIUM IP HOLDINGS, LLC (US) 2021-05-20 WO disclosed
WO-2021097139-A1 CHIRAL SYNTHESIS OF A TERTIARY ALCOHOL RECURIUM IP HOLDINGS, LLC (US) 2021-05-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12410204-B2 Chiral synthesis of a tertiary alcohol ADH1A, ADH1C, ADH5 WEE1 640/4885APP 4740/4885BACE1 4599/4885
US-20260028363-A1 CHIRAL SYNTHESIS OF A TERTIARY ALCOHOL ADH1A, ADH1C, ADH5 WEE1 92/4885APP 3942/4885BACE1 3850/4885
US-20230002426-A1 CHIRAL SYNTHESIS OF A TERTIARY ALCOHOL ADH1A, ADH1C, ADH5 WEE1 640/4885APP 4740/4885BACE1 4599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.