Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.52 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29204480 | 0.85 | SIGMAR1 (0.61) | SIGMAR1 | |
| SCHEMBL30484429 | 0.78 | EGLN1 (0.46) | OPRL1SIGMAR1 | |
| SCHEMBL30484402 | 0.76 | SIGMAR1 (0.56) | RORCOPRL1SIGMAR1 | |
| SCHEMBL30484446 | 0.75 | EGLN1 (0.43) | OPRL1SIGMAR1 | |
| SCHEMBL29204466 | 0.74 | EGLN1 (0.48) | OPRL1SIGMAR1 | |
| SCHEMBL29204460 | 0.74 | EGLN1 (0.48) | OPRL1SIGMAR1 | |
| SCHEMBL30484462 | 0.73 | EGLN1 (0.47) | OPRL1SIGMAR1 | |
| SCHEMBL29204511 | 0.72 | EGLN1 (0.46) | OPRL1SIGMAR1 | |
| SCHEMBL10374628 | 0.72 | OPRL1 (0.56) | OPRL1SIGMAR1 | |
| SCHEMBL30484482 | 0.72 | EGLN1 (0.46) | OPRL1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354897-B | Substituted 1,2, 4-triazole, pyridine and pyrimidine derivatives and application thereof in medicines | 华东师范大学 | 2024-10-15 | — | — | CN | disclosed |
| CN-116354897-A | Substituted 1,2, 4-triazole, pyridine and pyrimidine derivatives and application thereof in medicines | 华东师范大学 | 2023-06-30 | — | — | CN | disclosed |