Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29204513 | 0.89 | SIGMAR1 (0.58) | SIGMAR1TMEM97RORCOPRL1 | |
| SCHEMBL29204508 | 0.89 | SIGMAR1 (0.58) | SIGMAR1TMEM97RORC | |
| SCHEMBL29204493 | 0.86 | SIGMAR1 (0.59) | SIGMAR1TMEM97 | |
| SCHEMBL29204426 | 0.77 | SIGMAR1 (0.59) | SIGMAR1TMEM97 | |
| SCHEMBL29204462 | 0.77 | SIGMAR1 (0.59) | SIGMAR1TMEM97 | |
| SCHEMBL30484456 | 0.76 | RORC (0.52) | SIGMAR1RORCOPRL1 | |
| SCHEMBL29204475 | 0.75 | RORC (0.44) | SIGMAR1TMEM97RORCOPRL1 | |
| SCHEMBL31252997 | 0.75 | SIGMAR1 (0.41) | SIGMAR1TMEM97OPRL1 | |
| SCHEMBL30056578 | 0.74 | SIGMAR1 (1.00) | SIGMAR1TMEM97 | |
| SCHEMBL11949323 | 0.71 | RORC (0.55) | SIGMAR1RORCOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354897-B | Substituted 1,2, 4-triazole, pyridine and pyrimidine derivatives and application thereof in medicines | 华东师范大学 | 2024-10-15 | — | — | CN | disclosed |
| CN-116354897-A | Substituted 1,2, 4-triazole, pyridine and pyrimidine derivatives and application thereof in medicines | 华东师范大学 | 2023-06-30 | — | — | CN | disclosed |