Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 8/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716889 | 0.89 | AHCY (0.59) | AHCYADORA3ADORA2BHIF1ATMEM97 | |
| SCHEMBL226039 | 0.84 | AHCY (0.63) | AHCYADORA3ADORA2BHIF1ATMEM97 | |
| SCHEMBL5320373 | 0.82 | P2RY2 (0.63) | AHCYADORA3ADORA2BADORA1 | |
| SCHEMBL5327602 | 0.82 | AHCY (0.65) | AHCYADORA3ADORA2BHIF1ATMEM97 | |
| SCHEMBL787408 | 0.81 | AHCY (0.59) | AHCYADORA3ADORA2BADORA1 | |
| SCHEMBL6826848 | 0.81 | HSP90AA1 (0.62) | AHCYADORA3ADORA2BTSHRLMNA | |
| SCHEMBL22326785 | 0.81 | PRMT5 (0.64) | AHCYADORA3ADORA2BHIF1ATMEM97 | |
| SCHEMBL21413837 | 0.81 | PRMT5 (0.64) | AHCYADORA3ADORA2BHIF1ATMEM97 | |
| SCHEMBL22326787 | 0.81 | PRMT5 (0.64) | AHCYADORA3ADORA2BHIF1ATMEM97 | |
| SCHEMBL16300875 | 0.81 | PRMT5 (0.64) | AHCYADORA3ADORA2BHIF1ATMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010129294-A2 | SMALL MOLECULES SUPPORTING PLURIPOTENT CELL GROWTH AND METHODS THEREOF | SCHULZ THOMAS C (US) | 2010-11-11 | — | — | WO | claimed |