Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.41 |
| ▸ | SULT1A1 | P50225 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26947064 | 1.00 | MAOB (0.44) | MAOBHTTGAAL3MBTL1DYRK1A | |
| SCHEMBL26947058 | 0.85 | PTPN1 (0.46) | HTTGAAL3MBTL1DYRK1ACA2 | |
| SCHEMBL16666119 | 0.84 | PTPN1 (0.46) | HTTGAADYRK1ACA2 | |
| SCHEMBL30132337 | 0.83 | CYP1A2 (0.49) | HTTGAADYRK1ACA2 | |
| SCHEMBL17038133 | 0.83 | CYP1A2 (0.49) | HTTGAADYRK1ACA2 | |
| SCHEMBL15699765 | 0.81 | MAPT (0.52) | HTTGAAL3MBTL1 | |
| SCHEMBL25292392 | 0.80 | HTT (0.50) | MAOBHTTGAAL3MBTL1DYRK1A | |
| SCHEMBL31558326 | 0.79 | TP53 (0.45) | HTTL3MBTL1CA2CA12CA1 | |
| SCHEMBL15839260 | 0.79 | NPC1 (0.38) | MAOBGAAL3MBTL1EGFRCA2 | |
| SCHEMBL21889371 | 0.79 | CYP1A2 (0.47) | HTTGAADYRK1ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630544-B2 | Compound, α-synuclein aggregate binder, and use thereof | National Institutes for Quantum Science and Technology (JP) | 2026-05-19 | — | — | US | disclosed |
| WO-2025085387-A1 | SUBSTITUTED-ALKENYL-INDAZOLES FOR IMAGING AGGREGATED TAU IN TAUOPATHIES | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2025-04-24 | — | — | WO | disclosed |
| US-20230399323-A1 | NOVEL COMPOUND, a-SYNUCLEIN AGGREGATE BINDER, AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-12-14 | — | — | US | disclosed |
| EP-4206200-A1 | NOVEL COMPOUND, ALPHA-SYNUCLEIN AGGREGATE BINDER, AND USE THEREOF | National Institutes for Quantum Science and Technology (JP) | 2023-07-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399323-A1 | NOVEL COMPOUND, a-SYNUCLEIN AGGREGATE BINDER, AND USE THEREOF | SNCA, PARK7, ATXN2L | MAOB 1979/4885HTT 4/4885GAA 233/4885 |
| US-12630544-B2 | Compound, α-synuclein aggregate binder, and use thereof | SNCA, PARK7, MAPT | MAOB 3513/4885HTT 7/4885GAA 1669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.