Iodide

Iodide

SCHEMBL30486757

CCc1cccc(N)c1.I

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.56
MAOA P21397 2/20 0.56
CYP19A1 P11511 1/20 0.54
CYP3A4 P08684 3/20 0.50
CASP1 P29466 1/20 0.50
RECQL P46063 1/20 0.50
TP53 P04637 2/20 0.47
ALDH1A1 P00352 4/20 0.45
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
NPC1 O15118 1/20 0.45
MAPT P10636 1/20 0.45
HPGD P15428 1/20 0.45
RAB9A P51151 1/20 0.45
KMT2A Q03164 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
NOS3 P29474 1/20 0.43
NOS1 P29475 1/20 0.43
NOS2 P35228 1/20 0.43
KIF11 P52732 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33276 0.98
SCHEMBL29738346 0.98
Bromide SCHEMBL7343481 0.95 MAOB (0.56) MAOBMAOACYP19A1CYP3A4CASP1
Methane SCHEMBL28252202 0.95 MAOB (0.56) MAOBMAOACYP19A1CYP3A4CASP1
Hydrochloric Acid SCHEMBL2870154 0.95 MAOB (0.59) MAOBMAOACYP19A1CYP3A4CASP1
Cyanide SCHEMBL27784306 0.91 MAOB (0.52) MAOBMAOACYP19A1CYP3A4CASP1
SCHEMBL13484318 0.85 MAOA (0.56) MAOBMAOACYP19A1CYP3A4CASP1
SCHEMBL10554547 0.84 MAOA (0.46) MAOBMAOACYP19A1CYP3A4CASP1
SCHEMBL7205168 0.84 ALDH1A1 (0.48) MAOBMAOACYP19A1ALDH1A1KDM4E
SCHEMBL10559386 0.81 MAOA (0.43) MAOBMAOACYP19A1CYP3A4CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116406213-A Chemical method for inhibiting ion diffusion in perovskite battery 华东理工大学 2023-07-07 CN claimed