Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 14/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.81 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.81 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.81 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.81 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.81 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.81 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.43 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2740178 | 1.00 | SIRT1 (1.00) | SIRT1CHRM2ADRA2ACHRM1SLC6A2 | |
| SCHEMBL29488567 | 0.89 | SIRT1 (1.00) | SIRT1CHRM2ADRA2ACHRM1SLC6A2 | |
| SCHEMBL963877 | 0.89 | SIRT1 (1.00) | SIRT1CHRM2ADRA2ACHRM1SLC6A2 | |
| Hydrochloric Acid SCHEMBL16372055 | 0.89 | SIRT1 (0.98) | SIRT1CHRM2ADRA2ACHRM1SLC6A2 | |
| Hydrochloric Acid SCHEMBL30156752 | 0.89 | SIRT1 (0.98) | SIRT1CHRM2ADRA2ACHRM1SLC6A2 | |
| SCHEMBL2624783 | 0.86 | SIRT1 (1.00) | SIRT1CHRM2ADRA2ACHRM1SLC6A2 | |
| SCHEMBL11953437 | 0.86 | SIRT1 (0.77) | SIRT1CHRM2ADRA2ACHRM1SLC6A2 | |
| SCHEMBL2740282 | 0.85 | SIRT1 (0.82) | SIRT1CHRM2ADRA2ACHRM1SLC6A2 | |
| SCHEMBL2740356 | 0.85 | SIRT1 (1.00) | SIRT1CHRM2ADRA2ACHRM1SLC6A2 | |
| SCHEMBL2740355 | 0.84 | SIRT1 (0.79) | SIRT1CHRM2ADRA2ACHRM1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130140-A2 | PERSONALIZED METHODS OF TREATING CANCER | FAETH THERAPEUTICS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |