Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 15/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 1/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 1/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 1/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 1/20 | 1.00 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 1.00 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29488567 | 1.00 | SIRT1 (1.00) | SIRT1CHRM2ADRA2ACHRM1SLC6A2 | |
| Hydrochloric Acid SCHEMBL16372055 | 0.99 | SIRT1 (0.98) | SIRT1CHRM2ADRA2ACHRM1SLC6A2 | |
| Hydrochloric Acid SCHEMBL30156752 | 0.99 | SIRT1 (0.98) | SIRT1CHRM2ADRA2ACHRM1SLC6A2 | |
| SCHEMBL2740335 | 0.93 | SIRT1 (0.86) | SIRT1CHRM2ADRA2ACHRM1SLC6A2 | |
| SCHEMBL2740379 | 0.92 | SIRT1 (0.85) | SIRT1CHRM2ADRA2ACHRM1SLC6A2 | |
| SCHEMBL2624518 | 0.92 | SIRT1 (0.85) | SIRT1CHRM2ADRA2ACHRM1SLC6A2 | |
| SCHEMBL2740334 | 0.92 | SIRT1 (0.85) | SIRT1CHRM2ADRA2ACHRM1SLC6A2 | |
| SCHEMBL2740430 | 0.91 | SIRT1 (0.83) | SIRT1CHRM2ADRA2ACHRM1SLC6A2 | |
| SCHEMBL2624519 | 0.90 | SIRT1 (0.82) | SIRT1CHRM2ADRA2ACHRM1SLC6A2 | |
| SCHEMBL2740333 | 0.90 | SIRT1 (0.82) | SIRT1CHRM2ADRA2ACHRM1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 468 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250144056-A1 | ANTIMICROBIAL HOST DEFENSE PEPTIDE-INDUCING COMPOSITIONS AND METHODS OF PRODUCTION AND USE THEREOF | BOARD OF REGENTS FOR THE OKLAHOMA AGRICULTURAL AND MECH COLLEGES (US) | 2025-05-08 | — | — | US | claimed |
| EP-3474834-B1 | STIMULATING PLATELET FORMATION WITH BEZAFIBRATE, RESVERATROL OR SRT1720 TO TREAT THROMBOCYTOPENIA | THE GENERAL HOSPITAL CORP DBA MASSACHUSETTS GENERAL HOSPITAL (US) | 2025-04-09 | — | — | EP | claimed |
| CN-119488447-A | Application of SRT1720 in preparation of skin antioxidant repairing agent | 大连大学 | 2025-02-21 | — | — | CN | claimed |
| CN-119488524-A | Collagen regeneration preparation | 大连大学 | 2025-02-21 | — | — | CN | claimed |
| US-20250032581-A1 | COMPOSITIONS AND ARTICLES COMPRISING AN ADNF POLYPEPTIDE | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2025-01-30 | — | — | US | claimed |
| US-20240335473-A1 | USE OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR 1-ALPHA (PGC1ALPHA) AGONISTS TO IMPROVE EX VIVO EXPANSION OF TUMOR INFILTRATING LYMPHOCYTES (TILS) | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2024-10-10 | — | — | US | claimed |
| US-20240156973-A1 | OSTEOTROPIC COMPOSITIONS AND USES THEREOF | PURDUE RESEARCH FOUNDATION | 2024-05-16 | — | — | US | claimed |
| EP-4340890-A1 | OSTEOTROPIC COMPOSITIONS AND USES THEREOF | Purdue Research Foundation (US) | 2024-03-27 | — | — | EP | claimed |
| EP-3384007-B1 | IMPROVED METHODS FOR REPROGRAMING NON-PLURIPOTENT CELLS INTO PLURIPOTENT STEM CELLS | BEIHAO STEM CELL AND REGENERATIVE MEDICINE RES INSTITUTE CO LTD (CN) | 2024-03-27 | — | — | EP | claimed |
| US-20240041767-A1 | Mitochondria-Enriched Extracellular Vesicles | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) | 2024-02-08 | — | — | US | claimed |
| CN-114432309-A | Method for improving activity of nicotinamide phosphoribosyltransferase and composition thereof | 中国科学院深圳先进技术研究院 | 2022-05-06 | — | — | CN | claimed |
| CN-108934168-B | Improved methods for reprogramming non-pluripotent cells to pluripotent stem cells | 北昊干细胞与再生医学研究院有限公司 | 2022-05-03 | — | — | CN | claimed |
| US-20180362650-A1 | PD-1 SIGNAL INHIBITOR COMBINATION THERAPY | KYOTO UNIVERSITY (JP) | 2018-12-20 | — | — | US | claimed |
| WO-2017123161-A9 | INHIBITION OF INTRACELLULAR GROWTH OF MYCOBACTERIUM SPECIES AND ITS APPLICATIONS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-11-15 | — | — | WO | claimed |
| EP-3388084-A1 | PD-1 SIGNAL INHIBITOR COMBINATION THERAPY | Kyoto University (JP) | 2018-10-17 | — | — | EP | claimed |
| WO-2017123161-A1 | INHIBITION OF INTRACELLULAR GROWTH OF MYCOBACTERIUM SPECIES AND ITS APPLICATIONS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-07-20 | — | — | WO | claimed |
| US-20160145581-A1 | COMPOSITIONS AND METHODS FOR REPROGRAMING NON-PLURIPOTENT CELLS INTO PLURIPOTENT STEM CELLS | HONG GUAN, LTD. (CN) | 2016-05-26 | — | — | US | claimed |
| EP-3019596-A1 | COMPOSITIONS AND METHODS FOR REPROGRAMING NON- PLURIPOTENT CELLS INTO PLURIPOTENT STEM CELLS | Hong Guan Ltd. (CN) | 2016-05-18 | — | — | EP | claimed |
| US-20150133527-A1 | REGULATION OF CARDIAC SODIUM CHANNELS BY SIRT1 AND SIRT1 ACTIVATORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2015-05-14 | — | — | US | claimed |
| WO-2015003643-A1 | COMPOSITIONS AND METHODS FOR REPROGRAMING NON- PLURIPOTENT CELLS INTO PLURIPOTENT STEM CELLS | HONG GUAN LTD. (CN) | 2015-01-15 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240335473-A1 | USE OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR 1-ALPHA (PGC1ALPHA) AGONISTS TO IMPROVE EX VIVO EXPANSION OF TUMOR INFILTRATING LYMPHOCYTES (TILS) | PPARD, PPARA, PPARG | SIRT1 36/4885CHRM2 2598/4885ADRA2A 472/4885 |
| US-20160145581-A1 | COMPOSITIONS AND METHODS FOR REPROGRAMING NON-PLURIPOTENT CELLS INTO PLURIPOTENT STEM CELLS | AHCY, GSKIP, AHCYL1 | SIRT1 206/4885CHRM2 1550/4885ADRA2A 2486/4885 |
| US-20150133527-A1 | REGULATION OF CARDIAC SODIUM CHANNELS BY SIRT1 AND SIRT1 ACTIVATORS | SIRT1, SIRT5, SIRT3 | SIRT1 1/4885CHRM2 1303/4885ADRA2A 564/4885 |
| US-20240156973-A1 | OSTEOTROPIC COMPOSITIONS AND USES THEREOF | SOST, BMP2, BMP6 | SIRT1 4605/4885CHRM2 4218/4885ADRA2A 928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.