Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | ELANE | P08246 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.58 |
| ▸ | WNT3A | P56704 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | TPMT | P51580 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL139147 | 1.00 | MAPT (0.66) | MAPTALDH1A1ELANETSHRCTNNB1 | |
| SCHEMBL8317717 | 0.88 | MAPT (0.53) | MAPTALDH1A1ELANETSHRCTNNB1 | |
| SCHEMBL135295 | 0.87 | MAPT (0.51) | MAPTALDH1A1ELANETSHRCTNNB1 | |
| SCHEMBL12694462 | 0.87 | MEN1 (0.65) | MAPTALDH1A1ELANECYP1A2MEN1 | |
| SCHEMBL12694514 | 0.86 | ALDH1A1 (0.61) | MAPTALDH1A1ELANECYP1A2CYP2C19 | |
| SCHEMBL15353806 | 0.86 | MAPT (0.50) | MAPTALDH1A1ELANETSHRCTNNB1 | |
| SCHEMBL9902302 | 0.86 | HTT (0.59) | MAPTALDH1A1ELANETSHRCTNNB1 | |
| SCHEMBL28537504 | 0.84 | ALDH1A1 (0.52) | MAPTALDH1A1ELANETSHRCTNNB1 | |
| SCHEMBL7017185 | 0.84 | CTNNB1 (0.63) | MAPTALDH1A1ELANETSHRCTNNB1 | |
| SCHEMBL2089372 | 0.84 | PDE4B (0.56) | MAPTALDH1A1ELANEPDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118717736-A | Application of diphenyl propenone compound in preparation of schistosome prevention and treatment drugs and schistosome prevention and treatment drugs | 赣南师范大学 | 2024-10-01 | — | — | CN | disclosed |
| CN-116535356-A | 3-amino-5-phenyl-pyrazole derivative tubulin inhibitor and preparation and medical application thereof | 中国药科大学 | 2023-08-04 | — | — | CN | disclosed |