Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | ELANE | P08246 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.58 |
| ▸ | WNT3A | P56704 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | TPMT | P51580 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30487237 | 1.00 | MAPT (0.66) | MAPTALDH1A1ELANETSHRCTNNB1 | |
| SCHEMBL8317717 | 0.88 | MAPT (0.53) | MAPTALDH1A1ELANETSHRCTNNB1 | |
| SCHEMBL135295 | 0.87 | MAPT (0.51) | MAPTALDH1A1ELANETSHRCTNNB1 | |
| SCHEMBL12694462 | 0.87 | MEN1 (0.65) | MAPTALDH1A1ELANECYP1A2MEN1 | |
| SCHEMBL12694514 | 0.86 | ALDH1A1 (0.61) | MAPTALDH1A1ELANECYP1A2CYP2C19 | |
| SCHEMBL15353806 | 0.86 | MAPT (0.50) | MAPTALDH1A1ELANETSHRCTNNB1 | |
| SCHEMBL9902302 | 0.86 | HTT (0.59) | MAPTALDH1A1ELANETSHRCTNNB1 | |
| SCHEMBL28537504 | 0.84 | ALDH1A1 (0.52) | MAPTALDH1A1ELANETSHRCTNNB1 | |
| SCHEMBL7017185 | 0.84 | CTNNB1 (0.63) | MAPTALDH1A1ELANETSHRCTNNB1 | |
| SCHEMBL2089372 | 0.84 | PDE4B (0.56) | MAPTALDH1A1ELANEPDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021077194-A1 | PROCESS FOR THE PRODUCTION OF ANTITUMOUR PHARMACEUTICAL COMPOSITIONS USING PUSH-PULL BUTADIENES, COMPOUNDS AND USES THEREOF | ANHANGUERA EDUCACIONAL PARTICIPAÇÕES S/A (BR) | 2021-04-29 | — | — | WO | claimed |
| CN-116535356-A | 3-amino-5-phenyl-pyrazole derivative tubulin inhibitor and preparation and medical application thereof | 中国药科大学 | 2023-08-04 | — | — | CN | disclosed |
| US-20230130823-A1 | PROCESS FOR THE PRODUCTION OF ANTITUMOUR PHARMACEUTICAL COMPOSITIONS USING PUSH-PULL BUTADIENES, COMPOUNDS AND USES THEREOF | ANHANGUERA EDUCACIONAL PARTICIPAÇÕES S/A (BR) | 2023-04-27 | — | — | US | disclosed |
| US-20230130823-A1 | PROCESS FOR THE PRODUCTION OF ANTITUMOUR PHARMACEUTICAL COMPOSITIONS USING PUSH-PULL BUTADIENES, COMPOUNDS AND USES THEREOF | ANHANGUERA EDUCACIONAL PARTICIPAÇÕES S/A (BR) | 2023-04-27 | — | — | US | disclosed |
| WO-2021077194-A1 | PROCESS FOR THE PRODUCTION OF ANTITUMOUR PHARMACEUTICAL COMPOSITIONS USING PUSH-PULL BUTADIENES, COMPOUNDS AND USES THEREOF | ANHANGUERA EDUCACIONAL PARTICIPAÇÕES S/A (BR) | 2021-04-29 | — | — | WO | disclosed |
| EP-2430029-B1 | THIENO[2,3-B]PYRIDINE DERIVATIVES AS VIRAL REPLICATION INHIBITORS | UNIV LEUVEN KATH (BE) | 2018-01-10 | — | — | EP | disclosed |
| US-9499563-B2 | Thieno [2, 3-B] pyridine derivatives as viral replication inhibitors | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2016-11-22 | — | — | US | disclosed |
| CN-105367583-A | THIENO[2, 3-B]PYRIDINE DERIVATIVES AS VIRAL REPLICATION INHIBITORS | UNIV LEUVEN KATH | 2016-03-02 | — | — | CN | disclosed |
| CN-102459280-B | Thieno [2,3-b ] pyridine derivatives as inhibitors of viral replication | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2015-10-14 | — | — | CN | disclosed |
| US-20140296272-A1 | THIENO [2, 3-B] PYRIDINE DERIVATIVES AS VIRAL REPLICATION INHIBITORS | CISTIM LEUVEN VZW (BE) | 2014-10-02 | — | — | US | disclosed |
| EP-0945438-B1 | PYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-6180653-B1 | EATING DISORDERS; DIETETICS; ANTIDIABETIC AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-01-30 | — | — | US | disclosed |
| US-6057335-A | Pyrazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| US-6043246-A | Urea derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-03-28 | — | — | US | disclosed |
| EP-0955293-A1 | NOVEL UREA DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-11-10 | — | — | EP | disclosed |
| EP-0945438-A1 | PYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |
| EP-0945440-A1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |
| EP-0900223-A1 | THIENOPYRIDINE DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997040050-A1 | THIENOPYRIDINE DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |
| US-5453514-A | Diabetes | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1995-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230130823-A1 | PROCESS FOR THE PRODUCTION OF ANTITUMOUR PHARMACEUTICAL COMPOSITIONS USING PUSH-PULL BUTADIENES, COMPOUNDS AND USES THEREOF | BAD, BAX, PDCD4 | MAPT 3567/4885ALDH1A1 2558/4885ELANE 1375/4885 |
| US-20140296272-A1 | THIENO [2, 3-B] PYRIDINE DERIVATIVES AS VIRAL REPLICATION INHIBITORS | TYMP, DUT, MAVS | MAPT 2061/4885ALDH1A1 1925/4885ELANE 3096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.