Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694261 | 0.86 | DPP7 (0.44) | GNAI3GNAO1GNAI1DPP7DPP8 | |
| SCHEMBL1821347 | 0.76 | DPP7 (0.44) | DPP7DPP8DPP9DPP4KMT2A | |
| SCHEMBL5499007 | 0.72 | GSR (0.61) | GNAI3GNAO1GNAI1DPP7DPP8 | |
| SCHEMBL19088201 | 0.70 | GSR (0.55) | GNAI3GNAO1GNAI1DPP7DPP8 | |
| SCHEMBL5495401 | 0.70 | GSR (0.59) | GNAI3GNAO1GNAI1DPP7DPP8 | |
| SCHEMBL2694035 | 0.68 | DPP7 (0.64) | DPP7DPP8DPP9DPP4ITGB3 | |
| SCHEMBL29049118 | 0.68 | DPP7 (0.64) | DPP7DPP8DPP9DPP4ITGB3 | |
| SCHEMBL6752685 | 0.67 | DPP7 (0.62) | DPP7DPP8DPP9DPP4ITGB3 | |
| SCHEMBL16430142 | 0.66 | GSR (0.53) | GNAI3GNAO1GNAI1DPP7DPP8 | |
| SCHEMBL17982113 | 0.66 | GSR (0.53) | GNAI3GNAO1GNAI1DPP7DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727963-B2 | Synthetic peptide amides | CARA THERAPEUTICS, INC. (US) | 2010-06-01 | — | — | US | disclosed |