Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.44 |
| ▸ | DPP4 | P27487 | 4/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.44 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1821347 | 0.89 | DPP7 (0.44) | DPP7DPP4DPP8DPP9KMT2A | |
| SCHEMBL3048734 | 0.86 | GNAI3 (0.40) | DPP7DPP4DPP8ITGB3ITGA2B | |
| SCHEMBL6752685 | 0.79 | DPP7 (0.62) | DPP7DPP4DPP8ITGB3ITGA2B | |
| SCHEMBL10434878 | 0.78 | ITGB3 (0.39) | ITGB3ITGA2B | |
| SCHEMBL5499007 | 0.78 | GSR (0.61) | DPP7DPP4DPP8DPP9GSR | |
| SCHEMBL7700261 | 0.78 | PPID (0.38) | DPP7 | |
| SCHEMBL29049118 | 0.77 | DPP7 (0.64) | DPP7DPP4DPP8ITGB3ITGA2B | |
| SCHEMBL2694035 | 0.77 | DPP7 (0.64) | DPP7DPP4DPP8ITGB3ITGA2B | |
| SCHEMBL5495401 | 0.76 | GSR (0.59) | DPP7DPP4DPP8DPP9GSR | |
| SCHEMBL7301848 | 0.75 | MMP1 (0.46) | DPP7DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028829-A2 | PEPTIDE DEFORMYLASE INHIBITORS | QUESTCOR PHARMACEUTICALS, INC. (US) | 2002-04-11 | — | — | WO | claimed |