Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 9/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 9/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 9/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 9/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 9/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 9/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31020092 | 0.93 | GRIN2D (0.42) | KCNQ2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL25244708 | 0.93 | GRIN2D (0.42) | KCNQ2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30487432 | 0.81 | KCNQ2 (0.38) | KCNQ2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL25292456 | 0.81 | KCNQ2 (0.38) | KCNQ2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL25242314 | 0.80 | RAB9A (0.40) | KCNQ2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30487413 | 0.80 | RAB9A (0.40) | KCNQ2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30487421 | 0.79 | KCNQ2 (0.39) | KCNQ2JAK2JAK1TYK2JAK3 | |
| SCHEMBL25293874 | 0.76 | KCNQ2 (0.67) | KCNQ2 | |
| SCHEMBL30487477 | 0.76 | KCNQ2 (0.67) | KCNQ2 | |
| SCHEMBL25246524 | 0.74 | KCNQ2 (0.50) | KCNQ2GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118451079-A | Benzopiperidine derivative modulators, methods of preparation and uses thereof | 上海翰森生物医药科技有限公司 | 2024-08-06 | — | — | CN | disclosed |
| WO-2023125935-A1 | BENZOPYRIDINE DERIVATIVE REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |