Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25242314 | 1.00 | RAB9A (0.40) | RAB9AKCNQ2JAK2JAK1TYK2 | |
| SCHEMBL25247526 | 0.85 | RAB9A (0.42) | RAB9AKCNQ2JAK2JAK1TYK2 | |
| SCHEMBL30487352 | 0.85 | RAB9A (0.42) | RAB9AKCNQ2JAK2JAK1TYK2 | |
| Hydrochloric Acid SCHEMBL31020077 | 0.84 | RAB9A (0.41) | RAB9AKCNQ2JAK2JAK1TYK2 | |
| Ammonia Solution, Strong SCHEMBL25241047 | 0.84 | RAB9A (0.41) | RAB9AKCNQ2JAK2JAK1TYK2 | |
| SCHEMBL25244708 | 0.83 | GRIN2D (0.42) | KCNQ2JAK2JAK1TYK2JAK3 | |
| SCHEMBL31020092 | 0.83 | GRIN2D (0.42) | KCNQ2JAK2JAK1TYK2JAK3 | |
| SCHEMBL25245702 | 0.80 | KCNQ2 (0.48) | RAB9AKCNQ2JAK2JAK1TYK2 | |
| SCHEMBL30487391 | 0.80 | KCNQ2 (0.48) | RAB9AKCNQ2JAK2JAK1TYK2 | |
| SCHEMBL30487350 | 0.80 | KCNQ2 (0.38) | KCNQ2JAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119948023-A | Regulator containing piperidine polycyclic derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-118451079-A | Benzopiperidine derivative modulators, methods of preparation and uses thereof | 上海翰森生物医药科技有限公司 | 2024-08-06 | — | — | CN | disclosed |
| WO-2023125935-A1 | BENZOPYRIDINE DERIVATIVE REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |