Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TLR4 | O00206 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 2/20 | 0.35 |
| ▸ | BCKDK | O14874 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | ILK | Q13418 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8124099 | 0.76 | BCKDK (0.45) | ALDH1A1MAPTKDM4EHSD17B10GFER | |
| SCHEMBL1121782 | 0.76 | CCNB2 (0.44) | ALDH1A1MAPTKDM4EGFERAXL | |
| SCHEMBL12665748 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4EHSD17B10TLR4 | |
| SCHEMBL24898414 | 0.73 | BCKDK (0.40) | ALDH1A1MAPTKDM4EGFERLMNA | |
| SCHEMBL24848632 | 0.72 | ALDH1A1 (0.36) | ALDH1A1MAPTKDM4EGFERAXL | |
| SCHEMBL23478522 | 0.72 | KDM4E (0.48) | ALDH1A1MAPTKDM4EHSD17B10TLR4 | |
| SCHEMBL1121848 | 0.72 | ALDH1A1 (0.36) | ALDH1A1MAPTKDM4EGFERAXL | |
| SCHEMBL23478673 | 0.72 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EHSD17B10TLR4 | |
| SCHEMBL24898412 | 0.71 | BCKDK (0.47) | ALDH1A1MAPTKDM4EHSD17B10LMNA | |
| SCHEMBL30211547 | 0.71 | BCKDK (0.47) | ALDH1A1MAPTKDM4EHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118451079-A | Benzopiperidine derivative modulators, methods of preparation and uses thereof | 上海翰森生物医药科技有限公司 | 2024-08-06 | — | — | CN | disclosed |
| WO-2023125935-A1 | BENZOPYRIDINE DERIVATIVE REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |