Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 1.00 |
| ▸ | MAOA | P21397 | 18/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28813383 | 0.85 | MAOA (1.00) | MAOBMAOAKDM4EPOLBMAPT | |
| SCHEMBL30487592 | 0.81 | MAOA (1.00) | MAOBMAOAKDM4EPOLBMAPT | |
| SCHEMBL30487615 | 0.81 | MAOA (1.00) | MAOBMAOAKDM4EPOLBMAPT | |
| SCHEMBL13925642 | 0.80 | MAOA (0.77) | MAOBMAOAKDM4EPOLBMAPT | |
| SCHEMBL13925639 | 0.80 | MAOA (0.77) | MAOBMAOAKDM4EPOLBMAPT | |
| SCHEMBL30487583 | 0.80 | MAOA (0.77) | MAOBMAOAKDM4EPOLBMAPT | |
| SCHEMBL13925635 | 0.80 | MAOA (0.77) | MAOBMAOAKDM4EPOLBMAPT | |
| SCHEMBL23484269 | 0.77 | MAOB (0.62) | MAOBMAOAKDM4EPOLBMAPT | |
| SCHEMBL16870577 | 0.76 | MAOB (0.61) | MAOBMAOAKDM4EPOLBMAPT | |
| SCHEMBL30487586 | 0.74 | MAOA (1.00) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110872268-B | Isocoumarin derivative and preparation method and medicinal application thereof | 复旦大学 | 2023-07-25 | — | — | CN | disclosed |