Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 17/20 | 0.77 |
| ▸ | MAOB | P27338 | 8/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13925642 | 1.00 | MAOA (0.77) | MAOAMAOBKDM4EPOLBMAPT | |
| SCHEMBL28813383 | 0.87 | MAOA (1.00) | MAOAMAOBKDM4EPOLBMAPT | |
| SCHEMBL30487592 | 0.83 | MAOA (1.00) | MAOAMAOBKDM4EPOLBMAPT | |
| SCHEMBL30487615 | 0.83 | MAOA (1.00) | MAOAMAOBKDM4EPOLBMAPT | |
| SCHEMBL13925639 | 0.81 | MAOA (0.77) | MAOAMAOBKDM4EPOLBMAPT | |
| SCHEMBL13925635 | 0.81 | MAOA (0.77) | MAOAMAOBKDM4EPOLBMAPT | |
| SCHEMBL30487573 | 0.80 | MAOB (1.00) | MAOAMAOBKDM4EPOLBMAPT | |
| SCHEMBL13925647 | 0.79 | POLL (0.72) | MAOAMAOBKDM4EPOLBMAPT | |
| SCHEMBL13925645 | 0.78 | MAOA (0.78) | MAOAMAOBKDM4EPOLBMAPT | |
| SCHEMBL30487608 | 0.78 | MAOA (0.78) | MAOAMAOBKDM4EPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110872268-B | Isocoumarin derivative and preparation method and medicinal application thereof | 复旦大学 | 2023-07-25 | — | — | CN | disclosed |