Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | GAPDH | P04406 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825634 | 0.72 | KDM4E (0.35) | ALDH1A1KDM4EPOLBEDNRAMAPT | |
| SCHEMBL30424151 | 0.71 | BCAT2 (0.58) | BCAT2ALDH1A1KDM4EPOLBKMT2A | |
| SCHEMBL29996179 | 0.71 | BCAT2 (0.50) | BCAT2ALDH1A1KDM4EPOLBPLA2G10 | |
| SCHEMBL1379791 | 0.71 | BCAT2 (0.58) | BCAT2ALDH1A1KDM4EPOLBKMT2A | |
| SCHEMBL29543426 | 0.71 | BCAT2 (0.50) | BCAT2ALDH1A1KDM4EPOLBPLA2G10 | |
| SCHEMBL3346809 | 0.70 | BCAT2 (0.55) | BCAT2ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL29894413 | 0.70 | BCAT2 (0.49) | BCAT2ALDH1A1KDM4EPOLBPLA2G10 | |
| Hydrochloric Acid SCHEMBL29995989 | 0.70 | BCAT2 (0.49) | BCAT2ALDH1A1KDM4EPOLBPLA2G10 | |
| SCHEMBL27711486 | 0.70 | BCAT2 (0.49) | BCAT2ALDH1A1KDM4EPOLBPLA2G10 | |
| SCHEMBL16011605 | 0.68 | BCAT2 (0.59) | BCAT2ALDH1A1KDM4EPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444715-A1 | SOLID STATE FORMS OF LOTILANER AND PROCESS FOR PREPARATION THEREOF | Teva Pharmaceuticals International GmbH (CH) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107660-A1 | SOLID STATE FORMS OF LOTILANER AND PROCESS FOR PREPARATION THEREOF | TEVA PHARMACEUTICALS INTERNATIONAL GMBH (CH) | 2023-06-15 | — | — | WO | disclosed |