Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | EDNRB | P24530 | 2/20 | 0.30 |
| ▸ | EDNRA | P25101 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825600 | 0.79 | KDM4E (0.31) | KDM4ENPC1ALDH1A1RAB9APOLB | |
| SCHEMBL30488012 | 0.72 | BCAT2 (0.50) | KDM4ENPC1ALDH1A1RAB9APTGS1 | |
| SCHEMBL8890179 | 0.71 | PTPRC (0.31) | — | |
| SCHEMBL3828659 | 0.71 | CA2 (0.41) | PTGS2CA2CA9CA12CA1 | |
| SCHEMBL1548721 | 0.68 | POLB (0.52) | KDM4ENPC1ALDH1A1RAB9APOLB | |
| SCHEMBL27491067 | 0.68 | CA2 (0.34) | KDM4ENPC1ALDH1A1RAB9APOLB | |
| SCHEMBL28869430 | 0.68 | NPC1 (0.41) | NPC1RAB9APTGS2CA2CA9 | |
| SCHEMBL6168789 | 0.67 | CA2 (0.54) | PTGS2CA2CA9CA12CA1 | |
| SCHEMBL6702067 | 0.67 | PDPK1 (0.41) | KDM4EALDH1A1RAB9APTGS1PTGS2 | |
| SCHEMBL27536398 | 0.67 | BRD4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0165753-B1 | HERBICIDAL THIOPHENESULFONAMIDES AND PYRIDINESULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-12-11 | — | — | EP | disclosed |
| US-4723988-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-02-09 | — | — | US | disclosed |
| US-4684393-A | PLATN GROWTH REGULATORS | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1987-08-04 | — | — | US | disclosed |
| EP-0165753-A2 | Herbicidal thiophenesulfonamides and pyridinesulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-12-27 | — | — | EP | disclosed |