Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14944868 | 1.00 | LMNA (0.59) | LMNAKDM4EADRA2AADRA2CHIF1A | |
| SCHEMBL25269606 | 1.00 | LMNA (0.59) | LMNAKDM4EADRA2AADRA2CHIF1A | |
| SCHEMBL2423599 | 0.84 | SMN1; SMN2 (0.57) | LMNAKDM4ESMN1; SMN2GAASLC6A2 | |
| SCHEMBL4967847 | 0.81 | SMN1; SMN2 (0.53) | LMNAKDM4ESMN1; SMN2GAASLC6A2 | |
| (1S,2R)-Phenylpropanolamine SCHEMBL16992924 | 0.81 | KDM4E (0.77) | LMNAKDM4EADRA2AADRA2CHIF1A | |
| SCHEMBL15675981 | 0.80 | SMN1; SMN2 (0.50) | LMNAKDM4ESMN1; SMN2GAASLC6A2 | |
| SCHEMBL10500850 | 0.80 | SMN1; SMN2 (0.47) | LMNAKDM4ESMN1; SMN2GAASLC6A2 | |
| SCHEMBL1266179 | 0.79 | — | — | |
| SCHEMBL19632996 | 0.79 | — | — | |
| SCHEMBL177932 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107630-A2 | AMINO ALCOHOL COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |