SCHEMBL30488189

SCHEMBL30488189

O=C1CCc2cc(OCc3ccc(F)c(Cl)c3)ccc21

nearest known ligand 0.64

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOB P27338 20/20 0.64
MAOA P21397 15/20 0.64
GRM5 P41594 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25277311 1.00 MAOB (0.64) MAOBMAOAGRM5
SCHEMBL25224654 0.88 MAOB (0.64) MAOBMAOAGRM5
SCHEMBL30488307 0.88 MAOB (0.64) MAOBMAOAGRM5
SCHEMBL30488285 0.85 MAOB (0.60) MAOBMAOAGRM5
SCHEMBL30488246 0.85 MAOB (0.60) MAOBMAOA
SCHEMBL25277729 0.85 MAOB (0.60) MAOBMAOA
SCHEMBL25270439 0.85 MAOB (0.60) MAOBMAOAGRM5
SCHEMBL4419819 0.83 MAOB (0.85) MAOBMAOAGRM5
SCHEMBL25277089 0.82 MAOB (0.57) MAOBMAOAGRM5
SCHEMBL30488234 0.82 MAOB (0.57) MAOBMAOAGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4444697-A1 CARBOXYLIC ACID CONTAINING INDANYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES CELGENE CORPORATION (US) 2024-10-16 EP disclosed
CN-118632834-A Indanyl compounds containing carboxylic acids for the treatment of neurodegenerative diseases 细胞基因公司 2024-09-10 CN disclosed
WO-2023107563-A1 CARBOXYLIC ACID CONTAINING INDANYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES CELGENE CORPORATION (US) 2023-06-15 WO disclosed