SCHEMBL30488246

SCHEMBL30488246

Cc1ccc(COc2ccc3c(c2)CCC3=O)cc1Cl

nearest known ligand 0.60

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOB P27338 17/20 0.60
MAOA P21397 15/20 0.60
HRH3 Q9Y5N1 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25277729 1.00 MAOB (0.60) MAOBMAOAHRH3
SCHEMBL30488285 0.85 MAOB (0.60) MAOBMAOA
SCHEMBL30488189 0.85 MAOB (0.64) MAOBMAOA
SCHEMBL25277311 0.85 MAOB (0.64) MAOBMAOA
SCHEMBL25270439 0.85 MAOB (0.60) MAOBMAOA
SCHEMBL25276866 0.82 MAOB (0.63) MAOBMAOAHRH3
SCHEMBL30488234 0.82 MAOB (0.57) MAOBMAOA
SCHEMBL25277089 0.82 MAOB (0.57) MAOBMAOA
SCHEMBL30488207 0.82 MAOB (0.63) MAOBMAOAHRH3
SCHEMBL25224654 0.81 MAOB (0.64) MAOBMAOAHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240376048-A1 Carboxylic Acid Containing Indanyl Compounds for the Treatment of Neurodegenerative Diseases CELGENE CORPORATION (US) 2024-11-14 US disclosed
EP-4444697-A1 CARBOXYLIC ACID CONTAINING INDANYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES CELGENE CORPORATION (US) 2024-10-16 EP disclosed
CN-118632834-A Indanyl compounds containing carboxylic acids for the treatment of neurodegenerative diseases 细胞基因公司 2024-09-10 CN disclosed
WO-2023107563-A1 CARBOXYLIC ACID CONTAINING INDANYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES CELGENE CORPORATION (US) 2023-06-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240376048-A1 Carboxylic Acid Containing Indanyl Compounds for the Treatment of Neurodegenerative Diseases S1PR5, S1PR2, LPAR5 MAOB 2145/4885MAOA 2393/4885HRH3 606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.