Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 17/20 | 0.64 |
| ▸ | MAOA | P21397 | 15/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25224654 | 1.00 | MAOB (0.64) | MAOBMAOAHRH3GRM5ACHE | |
| SCHEMBL20809724 | 0.92 | MAOA (0.77) | MAOBMAOA | |
| SCHEMBL30488189 | 0.88 | MAOB (0.64) | MAOBMAOAGRM5 | |
| SCHEMBL25277311 | 0.88 | MAOB (0.64) | MAOBMAOAGRM5 | |
| SCHEMBL4419819 | 0.86 | MAOB (0.85) | MAOBMAOAGRM5 | |
| SCHEMBL20809506 | 0.82 | MAOB (0.55) | MAOBMAOAHRH3 | |
| SCHEMBL30488265 | 0.82 | MAOB (0.55) | MAOBMAOAHRH3 | |
| SCHEMBL4424278 | 0.82 | GABRG2 (0.52) | MAOBMAOAGRM5ACHE | |
| SCHEMBL25230739 | 0.81 | MAOB (0.85) | MAOBMAOAHRH3 | |
| SCHEMBL31185499 | 0.81 | MAOB (0.85) | MAOBMAOAHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444697-A1 | CARBOXYLIC ACID CONTAINING INDANYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | CELGENE CORPORATION (US) | 2024-10-16 | — | — | EP | disclosed |
| CN-118632834-A | Indanyl compounds containing carboxylic acids for the treatment of neurodegenerative diseases | 细胞基因公司 | 2024-09-10 | — | — | CN | disclosed |
| WO-2023107563-A1 | CARBOXYLIC ACID CONTAINING INDANYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | CELGENE CORPORATION (US) | 2023-06-15 | — | — | WO | disclosed |