Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 16/20 | 0.69 |
| ▸ | MAOA | P21397 | 9/20 | 0.69 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25226722 | 1.00 | MAOB (0.69) | MAOBMAOANR4A2MAPTPOLB | |
| SCHEMBL5638876 | 0.86 | MAOB (0.86) | MAOBMAOA | |
| SCHEMBL327001 | 0.82 | MAOB (0.84) | MAOBMAOA | |
| SCHEMBL25225245 | 0.81 | MAOB (0.86) | MAOBMAOA | |
| SCHEMBL31185507 | 0.81 | MAOB (0.86) | MAOBMAOA | |
| SCHEMBL30488232 | 0.80 | MAOB (0.60) | MAOBMAOANR4A2MAPTPOLB | |
| SCHEMBL25276866 | 0.79 | MAOB (0.63) | MAOBMAOA | |
| SCHEMBL30488207 | 0.79 | MAOB (0.63) | MAOBMAOA | |
| SCHEMBL22480966 | 0.78 | MRGPRX4 (0.68) | MAOBMAOAPOLBL3MBTL1 | |
| SCHEMBL6190278 | 0.77 | MAOB (0.72) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444697-A1 | CARBOXYLIC ACID CONTAINING INDANYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | CELGENE CORPORATION (US) | 2024-10-16 | — | — | EP | disclosed |
| CN-118632834-A | Indanyl compounds containing carboxylic acids for the treatment of neurodegenerative diseases | 细胞基因公司 | 2024-09-10 | — | — | CN | disclosed |
| WO-2023107563-A1 | CARBOXYLIC ACID CONTAINING INDANYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | CELGENE CORPORATION (US) | 2023-06-15 | — | — | WO | disclosed |