Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.37 |
| ▸ | MAT2A | P31153 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25305252 | 1.00 | KDM4E (0.38) | KDM4EHSD17B10NLRP3MAT2AKMT2A | |
| SCHEMBL25256486 | 1.00 | KDM4E (0.38) | KDM4EHSD17B10NLRP3MAT2AKMT2A | |
| SCHEMBL25302310 | 0.94 | KDM4E (0.41) | KDM4EHSD17B10NLRP3KMT2AALDH1A1 | |
| SCHEMBL30488599 | 0.94 | KDM4E (0.41) | KDM4EHSD17B10NLRP3KMT2AALDH1A1 | |
| SCHEMBL25302312 | 0.94 | KDM4E (0.41) | KDM4EHSD17B10NLRP3KMT2AALDH1A1 | |
| SCHEMBL30108757 | 0.84 | NLRP3 (0.47) | KDM4EHSD17B10NLRP3KMT2AALDH1A1 | |
| SCHEMBL28934427 | 0.84 | NLRP3 (0.47) | KDM4EHSD17B10NLRP3KMT2AALDH1A1 | |
| SCHEMBL28934430 | 0.84 | NLRP3 (0.47) | KDM4EHSD17B10NLRP3KMT2AALDH1A1 | |
| SCHEMBL25855246 | 0.83 | NLRP3 (0.55) | NLRP3MAT2A | |
| SCHEMBL25855086 | 0.82 | NLRP3 (0.38) | KDM4EHSD17B10NLRP3KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119798221-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-116410140-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2023-07-11 | — | — | CN | disclosed |