SCHEMBL30488555

SCHEMBL30488555

C#Cc1ccc(-c2nnc(N[C@@H]3CCCN(C)C3)nc2C)c(O)c1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IL1B P01584 8/20 0.52
NLRP3 Q96P20 14/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25303351 1.00 IL1B (0.52) IL1BNLRP3
SCHEMBL25303354 1.00 IL1B (0.52) IL1BNLRP3
SCHEMBL30834052 0.94 NLRP3 (0.45) IL1BNLRP3
SCHEMBL29030492 0.90 NLRP3 (0.56) IL1BNLRP3
SCHEMBL30488578 0.90 NLRP3 (0.56) IL1BNLRP3
SCHEMBL25856250 0.90 NLRP3 (0.56) IL1BNLRP3
SCHEMBL25856264 0.90 IL1B (0.51) IL1BNLRP3
SCHEMBL29030494 0.89 NLRP3 (0.52) IL1BNLRP3
SCHEMBL31548627 0.89 NLRP3 (0.52) IL1BNLRP3
SCHEMBL30488485 0.89 NLRP3 (0.52) IL1BNLRP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798221-A NLRP3 inflammation corpuscle inhibitor and application thereof 药捷安康(南京)科技股份有限公司 2025-04-11 CN disclosed
CN-116410140-A NLRP3 inflammation corpuscle inhibitor and application thereof 药捷安康(南京)科技股份有限公司 2023-07-11 CN disclosed