Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 8/20 | 0.42 |
| ▸ | IL1B | P01584 | 5/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | CCNK | O75909 | 4/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 4/20 | 0.35 |
| ▸ | CDK2 | P24941 | 4/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.35 |
| ▸ | CDK9 | P50750 | 3/20 | 0.35 |
| ▸ | CDK7 | P50613 | 2/20 | 0.35 |
| ▸ | CCNH | P51946 | 2/20 | 0.35 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25302745 | 1.00 | NLRP3 (0.42) | NLRP3IL1BEHMT2CCNKCDK12 | |
| SCHEMBL25302741 | 1.00 | NLRP3 (0.42) | NLRP3IL1BEHMT2CCNKCDK12 | |
| SCHEMBL30488544 | 1.00 | NLRP3 (0.42) | NLRP3IL1BEHMT2CCNKCDK12 | |
| SCHEMBL30517866 | 0.90 | FLT3 (0.33) | NLRP3IL1BEHMT2CCNKCDK12 | |
| SCHEMBL30834023 | 0.86 | NLRP3 (0.43) | NLRP3IL1BEHMT2CCNKCDK12 | |
| SCHEMBL30834000 | 0.85 | NLRP3 (0.42) | NLRP3IL1BEHMT2CCNKCDK12 | |
| SCHEMBL25299226 | 0.84 | IL1B (0.54) | NLRP3IL1B | |
| SCHEMBL25299227 | 0.84 | IL1B (0.54) | NLRP3IL1B | |
| SCHEMBL30488560 | 0.84 | IL1B (0.54) | NLRP3IL1B | |
| SCHEMBL31197268 | 0.84 | EHMT2 (0.35) | NLRP3EHMT2CCNKCDK12CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119798221-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-116410140-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2023-07-11 | — | — | CN | disclosed |