Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | CEL | P19835 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10847567 | 1.00 | ALDH1A1 (0.35) | ALDH1A1KDM4EHPGDHSD17B10APOBEC3G | |
| SCHEMBL10853509 | 0.97 | ALDH1A1 (0.32) | ALDH1A1KDM4EHPGDHSD17B10APOBEC3G | |
| SCHEMBL10846996 | 0.92 | PDE10A (0.31) | PDE10A | |
| SCHEMBL29919201 | 0.92 | PDE10A (0.31) | PDE10A | |
| SCHEMBL31091209 | 0.86 | PDE10A (0.39) | PDE10A | |
| SCHEMBL29919401 | 0.86 | PDE10A (0.39) | PDE10A | |
| SCHEMBL1787799 | 0.86 | PDE10A (0.39) | PDE10A | |
| SCHEMBL16577352 | 0.76 | PDE10A (0.36) | PDE10A | |
| SCHEMBL2059083 | 0.73 | KMT2A (0.39) | ALDH1A1KDM4EHPGDHSD17B10APOBEC3G | |
| SCHEMBL21306225 | 0.70 | HRH2 (0.33) | ALDH1A1KDM4EHPGDHSD17B10APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118541365-A | Antagonists of muscarinic acetylcholine receptor M4 | 范德堡大学 | 2024-08-23 | — | — | CN | disclosed |
| CN-116410140-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2023-07-11 | — | — | CN | disclosed |