Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23005292 | 1.00 | CYP1A2 (0.32) | CYP1A2CYP2D6CYP2C19HDAC8NOS3 | |
| SCHEMBL16289610 | 0.76 | CYP1A2 (0.32) | CYP1A2CYP2D6CYP2C19NOS3NOS2 | |
| SCHEMBL2303631 | 0.76 | NOS3 (0.38) | CYP1A2NOS3NOS2 | |
| SCHEMBL16289613 | 0.76 | UHRF1 (0.45) | NOS3NOS2 | |
| SCHEMBL23717247 | 0.76 | TRPV4 (0.32) | CYP1A2CYP2D6CYP2C19NOS3NOS2 | |
| SCHEMBL24998589 | 0.76 | TRPV1 (0.34) | CYP1A2CYP2D6CYP2C19NOS3NOS2 | |
| SCHEMBL21580673 | 0.75 | DRD1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL29072728 | 0.74 | RAF1 (0.37) | CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL628693 | 0.72 | — | — | |
| SCHEMBL21222944 | 0.72 | PDE4A (0.35) | HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111655700-B | Oxadiazolopyridine derivatives as ghrelin O-acyltransferase (GOAT) inhibitors | 勃林格殷格翰国际有限公司 | 2023-07-18 | — | — | CN | disclosed |