Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT2 | P23786 | 1/20 | 0.48 |
| ▸ | CPT1A | P50416 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25290141 | 1.00 | CPT2 (0.48) | CPT2CPT1ACASP3POLBSENP7 | |
| SCHEMBL25255606 | 0.76 | CPT2 (0.46) | CPT2CPT1ACASP3POLBSENP7 | |
| SCHEMBL29497022 | 0.76 | CPT2 (0.46) | CPT2CPT1ACASP3POLBSENP7 | |
| SCHEMBL30700470 | 0.69 | CPT2 (0.49) | CPT2CPT1APOLBKMT2ATSHR | |
| SCHEMBL23149068 | 0.69 | GRM5 (0.45) | CASP3POLBSENP7SENP6TSHR | |
| SCHEMBL25254795 | 0.69 | NPSR1 (0.32) | CPT1AKMT2AMEN1LMNAHTT | |
| SCHEMBL25297083 | 0.67 | CPT2 (0.46) | CPT2CPT1ACASP3POLBKMT2A | |
| SCHEMBL29496965 | 0.67 | CPT2 (0.46) | CPT2CPT1ACASP3POLBKMT2A | |
| SCHEMBL12224331 | 0.66 | LMNA (0.56) | CPT2CPT1ACASP3LMNA | |
| SCHEMBL12197778 | 0.66 | CASP3 (0.46) | CPT2CPT1ACASP3POLBCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4208456-A1 | HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2023-07-12 | — | — | EP | disclosed |