Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | GRM8 | O00222 | 1/20 | 0.40 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25256743 | 1.00 | MEN1 (0.49) | MEN1KMT2AHSD17B10L3MBTL1ABL1 | |
| SCHEMBL5365741 | 0.90 | ABL1 (0.50) | MEN1KMT2AL3MBTL1ABL1SMN1; SMN2 | |
| SCHEMBL5357758 | 0.85 | ABL1 (0.49) | MEN1KMT2AHSD17B10ABL1SMN1; SMN2 | |
| SCHEMBL5367633 | 0.85 | P2RX3 (0.48) | MEN1KMT2AL3MBTL1ABL1SMN1; SMN2 | |
| SCHEMBL15880384 | 0.82 | KMT2A (0.60) | MEN1KMT2AL3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL31697202 | 0.81 | MAPK10 (0.46) | L3MBTL1ABL1LMNAMAPTTDP1 | |
| SCHEMBL5373256 | 0.81 | PABPC1 (0.57) | MEN1KMT2AL3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL22208638 | 0.81 | MAPK10 (0.46) | L3MBTL1ABL1LMNAMAPTTDP1 | |
| SCHEMBL25250610 | 0.78 | ABL1 (0.37) | MEN1KMT2AABL1SMN1; SMN2S1PR4 | |
| SCHEMBL5363242 | 0.77 | GAA (0.51) | MEN1KMT2AL3MBTL1SMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4208456-A1 | HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2023-07-12 | — | — | EP | disclosed |