Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UPP1 | Q16831 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | DPYD | Q12882 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1201107 | 0.74 | KDM4E (0.53) | UPP1KDM4EALDH1A1CRHBPCRHR2 | |
| SCHEMBL3037924 | 0.74 | KDM4E (0.49) | UPP1KDM4EALDH1A1CRHBPCRHR2 | |
| SCHEMBL8064436 | 0.71 | PIM1 (0.56) | UPP1KDM4EALDH1A1CRHBPCRHR2 | |
| SCHEMBL9700724 | 0.70 | KDM4E (0.66) | UPP1KDM4EALDH1A1CRHBPCRHR2 | |
| SCHEMBL5824339 | 0.70 | UPP1 (0.53) | UPP1KDM4EALDH1A1MCL1DPYD | |
| SCHEMBL9614840 | 0.70 | UPP1 (1.00) | UPP1KDM4EALDH1A1CRHBPCRHR2 | |
| SCHEMBL5117155 | 0.69 | CRHBP (0.54) | UPP1KDM4EALDH1A1CRHBPCRHR2 | |
| SCHEMBL810681 | 0.69 | KDM4E (0.67) | UPP1KDM4EALDH1A1CRHBPCRHR2 | |
| SCHEMBL10751137 | 0.69 | KDM4E (0.49) | UPP1KDM4EALDH1A1CRHBPCRHR2 | |
| SCHEMBL17844413 | 0.68 | KDM4E (0.47) | UPP1KDM4EALDH1A1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6776930-B2 | POLYMER BONDED TO DYE | EASTMAN KODAK COMPANY | 2004-08-17 | — | — | US | claimed |
| US-20010023938-A1 | Polymer bonded to dye | ALLEN MAX (US) | 2001-09-27 | — | — | US | claimed |
| US-6197223-B1 | REACTING DIACIDIC MONOMER HAVING FORMULA H--A--H, COMPRISING 1 TO 100 MOLE % OF LIGHT-ABSORBING MONOMER HAVING A LIGHT ABSORPTION MAXIMUM BETWEEN 300 NM AND 1200 NM AND 99-0 MOLE % OF A NON-LIGHT ABSORBING MONOMER WITH ORGANIC COMPOUND | EASTMAN CHEMICAL COMPANY | 2001-03-06 | — | — | US | claimed |
| EP-0948570-A1 | METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 1999-10-13 | — | — | EP | claimed |
| WO-1998023690-A9 | METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS | — | 1998-09-17 | — | — | WO | claimed |
| WO-1998023690-A1 | METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 1998-06-04 | — | — | WO | claimed |
| EP-0605566-A1 | LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH | EASTMAN CHEMICAL COMPANY (US) | 1994-07-13 | — | — | EP | claimed |
| WO-1993006147-A1 | LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH | EASTMAN KODAK COMPANY (US) | 1993-04-01 | — | — | WO | claimed |
| US-5194463-A | LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH | EASTMAN KODAK COMPANY (US) | 1993-03-16 | — | — | US | claimed |
| EP-0009299-A1 | Colour stabilized organic material | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-04-02 | — | — | EP | claimed |
| US-9700547-B2 | Use of 6-hydroxy-2-pyridones and derivatives thereof for preparing a pharmaceutical composition that acts by inhibiting the human uridine phosphorylase enzyme | UNIÃO BRASILEIRA DE EDUCAÇÃO E ASSISTÊNCIA, MANTENEDORA DA PUCRS (BR) | 2017-07-11 | — | — | US | disclosed |
| EP-3042657-A1 | USE OF 6-HYDROXY-2-PYRIDONES AND DERIVATIVES THEREOF FOR PREPARING A PHARMACEUTICAL COMPOSITION THAT ACTS BY INHIBITING THE HUMAN URIDINE PHOSPHORYLASE ENZYME | UNIÃO BRASILEIRA DE EDUCAÇAO E ASSISTÊNCIA- MANTENEDORA DA PUCRS (BR) | 2016-07-13 | — | — | EP | disclosed |
| US-20160193197-A1 | USE OF 6-HYDROXY-2-PYRIDONES AND DERIVATIVES THEREOF FOR PREPARING A PHARMACEUTICAL COMPOSITION THAT ACTS BY INHIBITING THE HUMAN URIDINE PHOSPHORYLASE ENZYME | UNIÃO BRASILEIRA DE EDUCAÇÃO E ASSISTÊNCIA, MANTENEDORA DA PUCRS (BR) | 2016-07-07 | — | — | US | disclosed |
| WO-2015031968-A1 | USE OF 6-HYDROXY-2-PYRIDONES AND DERIVATIVES THEREOF FOR PREPARING A PHARMACEUTICAL COMPOSITION THAT ACTS BY INHIBITING THE HUMAN URIDINE PHOSPHORYLASE ENZYME | UNIÃO BRASILEIRA DE EDUCAÇÃO E ASSISTÊNCIA, MANTENEDORA DA PUCRS (BR) | 2015-03-12 | — | — | WO | disclosed |
| US-7754862-B2 | Multi-chromophoric AZO pyridone colorants | XEROX CORPORATION (US) | 2010-07-13 | — | — | US | disclosed |
| US-4225492-A | Water-soluble disazo dyestuffs, prepared from unsymmetrical heterocyclic diamines | CASSELLA AKTIENGESELLSCHAFT (DE) | 1980-09-30 | — | — | US | disclosed |
| EP-0009299-A1 | Colour stabilized organic material | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-04-02 | — | — | EP | disclosed |
| US-4144231-A | Soluble trisazo dyestuffs containing a 2-phenyl-benzimidazolyl, -benzoxazolyl or -benzthiazolyl middle component | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-03-13 | — | — | US | disclosed |
| US-4096145-A | DYES FOR RESINS AND POLYESTER TEXTILES | BASF AKTIENGESELLSCHAFT (DT) | 1978-06-20 | — | — | US | disclosed |
| US-3957749-A | WATER-INSOLUBLE MONOAZO PYRIDINE DYES | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160193197-A1 | USE OF 6-HYDROXY-2-PYRIDONES AND DERIVATIVES THEREOF FOR PREPARING A PHARMACEUTICAL COMPOSITION THAT ACTS BY INHIBITING THE HUMAN URIDINE PHOSPHORYLASE ENZYME | UPP1, PNP, TYMP | UPP1 1/4885KDM4E 1417/4885ALDH1A1 515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.