SCHEMBL30489052

SCHEMBL30489052

O=S1(=O)NCNc2cc(Cl)ccc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.53
CA1 P00915 5/20 0.53
LMNA P02545 2/20 0.53
CYP2C9 P11712 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
THRB P10828 1/20 0.53
APEX1 P27695 1/20 0.53
HTR2B P41595 1/20 0.53
PMP22 Q01453 1/20 0.53
CA12 O43570 6/20 0.49
CA9 Q16790 5/20 0.49
CHEK1 O14757 1/20 0.43
DAPK3 O43293 1/20 0.43
MAP4K4 O95819 1/20 0.43
RET P07949 1/20 0.43
PIM1 P11309 1/20 0.43
LTK P29376 1/20 0.43
GRK5 P34947 1/20 0.43
CSNK1A1 P48729 1/20 0.43
CDK8 P49336 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14351477 1.00 CA2 (0.53) CA2CA1LMNACYP2C9SMN1; SMN2
SCHEMBL27845505 0.87 CA2 (0.51) CA2CA1LMNACYP2C9SMN1; SMN2
SCHEMBL15998269 0.78 CA2 (0.50) CA2CA1LMNACYP2C9SMN1; SMN2
SCHEMBL14340040 0.75 CA2 (0.61) CA2CA1LMNACYP2C9SMN1; SMN2
SCHEMBL8429639 0.74 CA2 (0.60) CA2CA1LMNACYP2C9SMN1; SMN2
SCHEMBL8623901 0.74 CA2 (0.49) CA2CA1LMNACYP2C9SMN1; SMN2
SCHEMBL14679025 0.74 CA2 (0.50) CA2CA1LMNACYP2C9SMN1; SMN2
SCHEMBL13244816 0.74 CA2 (0.50) CA2CA1LMNACYP2C9SMN1; SMN2
SCHEMBL19166754 0.74 CA2 (0.64) CA2CA1LMNACYP2C9SMN1; SMN2
SCHEMBL9289749 0.73 CA1 (0.44) CA2CA1LMNACYP2C9SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116396193-A Method for preparing alpha-sulfonamido acetals from fatty aldehydes and sulfonamides 西北工业大学 2023-07-07 CN claimed
CN-116396193-A Method for preparing alpha-sulfonamido acetals from fatty aldehydes and sulfonamides 西北工业大学 2023-07-07 CN disclosed