Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 8/20 | 0.84 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.84 |
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.73 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.73 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.73 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | UCK2 | Q9BZX2 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15078006 | 0.74 | TP53 (0.77) | POLBTDP1MAPTTP53 | |
| SCHEMBL7506789 | 0.69 | L3MBTL1 (0.54) | TDP1MAPTMEN1KMT2ATP53 | |
| SCHEMBL13253112 | 0.67 | KMT2A (0.81) | POLBTDP1MAPTMEN1KMT2A | |
| SCHEMBL14680333 | 0.65 | POLB (0.51) | POLBTDP1MAPTTP53 | |
| SCHEMBL7500631 | 0.62 | MAPT (0.52) | POLBTDP1MAPTMEN1KMT2A | |
| SCHEMBL23657914 | 0.60 | TDP1 (0.85) | POLBTDP1MAPTMEN1KMT2A | |
| SCHEMBL1528709 | 0.60 | MAPT (0.62) | POLBTDP1MAPTMEN1KMT2A | |
| SCHEMBL14627781 | 0.59 | MAPT (0.54) | POLBTDP1MAPTMEN1KMT2A | |
| SCHEMBL28407262 | 0.59 | POLB (0.54) | POLBTDP1MAPTMEN1KMT2A | |
| SCHEMBL14208824 | 0.59 | NPC1 (0.69) | POLBMAPTMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112939947-B | PARP7 small molecule inhibitor compound and application thereof | 中国医科大学 | 2023-07-18 | — | — | CN | disclosed |