Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.31 |
| ▸ | CHRNG | P07510 | 1/20 | 0.31 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CHRND | Q07001 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25244236 | 0.82 | PTGS2 (0.42) | PTGS1PTGS2SLC6A2SLC6A3 | |
| SCHEMBL25212301 | 0.77 | PTGS2 (0.39) | PTGS1PTGS2 | |
| SCHEMBL28783504 | 0.73 | PTGS1 (0.36) | PTGS1PTGS2SIRT2SIRT1 | |
| SCHEMBL1959392 | 0.71 | PTGS2 (0.45) | PTGS1PTGS2SLC6A2SLC6A3 | |
| SCHEMBL25215204 | 0.69 | BCL2L1 (0.51) | PTGS1PTGS2SLC6A2SLC6A3 | |
| SCHEMBL22325211 | 0.68 | BCL2L1 (0.40) | PTGS1PTGS2SLC6A2SLC6A3 | |
| SCHEMBL26648644 | 0.68 | BCL2L1 (0.40) | PTGS1PTGS2SLC6A2SLC6A3 | |
| SCHEMBL25212842 | 0.66 | PTGS1 (0.37) | PTGS1PTGS2SLC6A2SLC6A3 | |
| SCHEMBL25308773 | 0.66 | PTGS1 (0.43) | PTGS1PTGS2SLC6A3SIRT2SIRT1 | |
| SCHEMBL25308772 | 0.66 | PTGS1 (0.43) | PTGS1PTGS2SLC6A3SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116419753-A | Heterocyclic compounds as BCL-2 inhibitors | 北京诺诚健华医药科技有限公司 | 2023-07-11 | — | — | CN | disclosed |